The ultimate goal is organ transplantation without rejection and without immunosuppression.

Cooperation Partners


IAV GmbH is one of the leading providers of development services and consulting for development processes in automotive engineering; with approximately 5,800 employees, it is one of the biggest employers in Lower Saxony. The cooperation takes place mainly with the mechatronics division, which has more than 25 years of expertise in software and tool development as well as control engineering. The division includes more than 500 highly qualified employees who provide key services in developing new control and management concepts, primarily in the automotive sector but more recently also in decentralized and renewable energy generation. IAV is specialized in the non-linear control of mechatronic systems and thermodynamic processes. Their experience in non-linear control of compact systems under different operating modes and production conditions is a unique local competence that benefits the project. Of particular relevance for this project is the extensive application practice of status and parameter estimators as well as model predictive controls and model-based diagnostics. The integration of IAV results in a strong networking within the metropolitan region of Hannover-Braunschweig-Göttingen-Wolfsburg, which can realize an enormous potential in the development of medical engineering by professionalizing the knowledge network. IAV is particularly involved in subproject 2 by modulating the nonlinear multi-variable dependencies. 

Imusyn GmbH & Co. KG

Imusyn GmbH & Co. KG is a biotechnology company that provides support for allogeneic cell therapies. Research, development and production focus on polymorphic genetic systems for innovative diagnostic and therapeutic approaches in the field of cell, tissue and organ transplantation. Based on proprietary genetic engineering processes, recombinant proteins of polymorphic genetic systems are developed and produced in high-throughput and massive parallel processes that enable targeted diagnostics as well as personalized therapy in allogeneic treatment protocols. The technologies used meet international customer requirements for medical diagnostics and life science markets. Imusyn is a very research-active SME located in the Medical Park Hanover in the immediate vicinity of Hannover Medical School. Imusyn is particularly involved in subproject 1 via large-scale vector production

Kai Ole Petersen Film GmbH (KOPF)

Kai Ole Petersen of Kai Ole Petersen Film GmbH (KOPF) is an outstanding filmmaker and photographer with a focus on image films. In addition to numerous productions for Continental, Nike, Pelikan and VWN, he has extensive media experience in the production of informational, educational and scientific films on medical subjects. Hanover-based KOPF has extensive experience in the cinematic implementation of complex medical themes and has a large repertoire of animation technologies at its disposal to present factual contexts in an understandable way even beyond the professional community. KOPF is involved in subprojects 1 and 2 through film production for multimedia networks in both the public and professional circles. 

SKC Beratungsgesellschaft mbH

SKC Beratungsgesellschaft mbH is specialized in the markets of the pharmaceutical industry, medical technology and biotechnology and considers the aspects of market access, market opportunities and reimbursability by the health care system. SKC's vision is an efficient and affordable healthcare system that focuses on the best possible patient treatment. SKC is distinguished by a very specific combination of scientific and medical expertise with many years of sound practical experience in strategic management consulting. Through an interdisciplinary team of sociologists, health care professionals, economists, biomedical scientists and medical engineers, SKC is able to develop a deep understanding of the relevant subject. SKC has extensive experience with the reimbursement mechanisms for medical devices in the EU and especially in Germany, the largest EU market for medical devices. SKC has extensive experience working with the Federal Joint Committee (Gemeinsamer Bundesausschuss, G-BA), the National Association of Statutory Health Care Funds (Spitzenverband der Gesetzlichen Krankenversicherung, GKV-SV), the Institute for Hospital Remuneration (Institut für das Entgelttsystem im Krankenhaus, InEK) and the Institute for Quality and Efficiency in Health Care (Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, IQWiG). SKC is particularly involved in subproject 3 through the analysis of the marketability of the ex vivo organ engineering procedure.